ANTIBODY RESPONSE IN NEWBORNS TO DIFFERENT DOSAGES OF HEPATITIS B VACCINES

can Isolated hepatitis B core antibody in HIV-infected patients response to hepatitis B vaccine help to elucidate the cause?

STUDIES ON HEPATITIS B VACCINES

HBs vaccines were prepared by three different methods: 1) Heat inactivation (Krugman, et.al 1971)2) Ammonium sulphate precipitation followed by column chromatography (Sephadex G-200) 3) PEG-6000 (polyethylene glycol) precipitation followed by column chromatography using Sephadex G-200. Their efficacy was studied in guinea pigs, and the results compared with commercial Japanese vaccine (Gr...

Immunogenicity and Economic Evaluation of Different Recombinant Hepatitis–b Vaccines in Different Dosages, Schedules, and Routes of Administration

Objective: To measure the immunogenic response produced by recombinant DNA derived vaccines in different dosages, schedules, and routes of administration. Another objective was to evaluate the minimum dosage and compliant schedule of recombinant DNA derived vaccine required to produce effective immune response and its economic evaluation in the adult population. Methodology: Five hundred fifty ...

Antibody response to hepatitis B vaccination.

Mathematical model of the antibody response to hepatitis B vaccines: implications for reduced schedules.

One of the cardinal features of the immune response is immune memory: the size of the secondary antibody response to vaccination reflects the amount of immune memory that has been generated in an individual by the priming dose. We construct a mathematical model of the generation of immune memory and antibody in response to hepatitis B vaccines. The model predictions are compared to post-vaccina...